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Hemoperfusion Cartridge (MG150 / MG250 / MG350)

The MG Disposable Hemoperfusion Cartridge is a sterile, non-pyrogenic, single-use device designed to remove the middle-to-large molecular substances such as cytokines. This product contains adsorbent polymer beads that adsorb the middle-to-large molecular substances as blood passes through the device. This product is placed in a blood pump circuit.
This product is expected to provide hemoperfusion, in order to remove medium and large molecular substances (such as cytokines) from the blood and improve prognosis, with indication of adjuvant treatment for End-stage Renal Disease (ESRD), Sepsis.

FEATURES

  • The mask conforms to the physiological shape of the face;
  • Good sealing performance, soft and comfortable;
  • Standard connector;
  • Different colors distinguish different specifications, which is easy to identify;
  • It has a removable endoscope type.

FEATURES

The MG Series hemoperfusion cartridges from Biosun Medical are designed for broad-spectrum adsorption of toxins in critical care settings, particularly targeting conditions like sepsis, drug overdose, and liver failure. Here are the key features based on available technical information and clinical use.

Absorbent

Macroporous Adsorption Resin The MG cartridges use specially treated polymeric resins with high surface area and controlled pore size (e.g., MG150, MG250, MG350). This enables efficient adsorption of mid-to-large molecular weight toxins (5,000–50,000 Daltons). Bead Surface Modification - Prevents clotting by repelling platelets/proteins. - Maintains adsorption efficiency by minimizing protein fouling.

Targeted Toxin Removal

Endotoxins (LPS): Critical for sepsis management. Inflammatory Cytokines: TNF-α, IL-6, IL-1β (key drivers of cytokine storms). Drugs/Toxins: Barbiturates, chemotherapeutic agents, mushroom toxins, etc. Bilirubin & Bile Acids: Useful in liver failure support. Myoglobin/UREMIC Toxins: Supplemental clearance in rhabdomyolysis or kidney injury.

Absorption Mechanism

Toxins (middle and large molecular , protein-bound toxins) diffuse into pores → trapped via van der Waals forces/hydrophobic interactions.

Practical Clinical Applications

ESRD: Adsorbs metabolic products and uremic toxins produced by renal failure patient Sepsis/SIRS: Adsorbs endotoxins and cytokines. Acute Intoxications: Rapid removal of lipophilic drugs/poisons. Liver Failure Support: Reduces bilirubin and ammonia. Adjuvant Therapy in MODS: Mitigates inflammatory mediators in multi-organ dysfunction.

Mode of Action

Hemoperfusion (HP), Hemoperfusion + Hemodialysis (HP+HD), Hemoperfusion + CRRT (HP+CRRT)

High Specific Bilirubin Absorption column information

SPECIFICATIONS

Single units: packaged with a sterilization bag, which is composed by PET/PP paper and TYVEK paper.
Secondary packaging: Single layer corrugated paper.
Tertiary packaging: Double walled corrugated board.

 Number of piecesDimensions
Box1/
MG150 Shipping Carton20490*415*220
MG250 Shipping Carton10490*225*215
MG350 Shipping Carton10500*270*210
Specification Blood compartment volume (mL)Adsorbent volume (mL)
MG15080≤V≤130 150
MG250110≤V≤160 250
MG350 150≤V≤200 350

DOCUMENTS

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